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Stoptions.ai›Tickers›AMGN
Last updated: Friday, May 22, 2026 · 9:31 AM ET
↻ Next update: Monday, May 25, 2026 · 9:31 AM ET

AMGNStock and Options Trade Setup — Amgen Inc.AMGN logo

Nasdaq 100 · Large-Cap Biotechnology & Drug Development · High-liquidity options · Large cap · ~$155B

▲ Bullish setupHealth CareBiotechnologyLow risk↑ Score +4 vs last update
71
Amora Edge Score
71
Top 32% of today's scan
↑ +4 vs last update
Composite of EMA, RSI, RS vs SPY & volume · updated every 72h
69
AMGN Win Rate
69%
8 of 12 AMGN setups hit target in 2026
Tracks completed Stoptions setups on this ticker since Jan 2026
Why we cover AMGN

Amgen is the quality defensive anchor of the biotech sector — a proven late-stage pipeline, $9B+ in annual free cash flow, and a 3%+ dividend yield make it a compounder that large institutions own through every cycle. The recent Horizon Therapeutics acquisition added the high-growth TEPEZZA and Krystexxa franchises. The bigger emerging story is MariTide — Amgen's injectable GLP-1/GIP obesity drug candidate — which has shown differentiated weight maintenance data and monthly dosing convenience versus weekly competitors. A pipeline readout on MariTide in late 2026 is a potential binary catalyst. The stock is defensively priced, with earnings well-supported by biosimilar-resistant core franchises. Low beta and consistent buybacks make it a reliable non-consensus long against more speculative biotech peers.

Score History & Signal Changelog

Preview data

This page is updated every 72 hours with the latest Scan results. Each data point below represents one complete algorithmic snapshot in time.

Score progression across 4 updates
Solid = composite · dashed = components
Signal Changelog
DateUpdateScoreDeltaKey change
May 5#1 Created59—Page created. Defensive biotech setup emerging; EMA structure aligned.
May 9#2 Update63+4Healthcare sector rotation supporting AMGN. MariTide pipeline interest growing.
May 14#3 Update67+4Volume above average; institutional positioning ahead of pipeline catalyst.
May 19#4 Current71+4All signals active. Quality defensive setup confirmed; elevated to Strong tier.

Signal Breakdown

EMA Cross
Active
18/25
Above both EMAs; steady uptrend with 20-day EMA acting as dynamic support
RSI Zone
Active
18/25
RSI at 62 — momentum zone; benefiting from biotech sector rotation
RS vs SPY
Active
17/25
Outperforming SPY +2.6pp; healthcare defensive rotation adding relative strength
Volume Surge
Active
18/25
1.6× 20-day avg; institutional accumulation on GLP-1 pipeline catalyst approach

Today's Trade Card

Setup
AMGN $305 CALL
Expires Jul 18, 2026
Premium
$6.40
Target
+65% premium
Stop loss
-42% premium
Breakeven
$311.4
Win prob.
56%
Sizing: Risk ≤ 1% of account
Greeks
Delta
0.40
Theta
-0.10
IVR
24%
IVR class
Low
Loading…

Options Profile

Avg IV (30d)
28%
IVR range (52-wk)
16–48%
Put/call ratio
0.76
Avg daily vol.
18K contracts
Open interest
240K contracts
Next earnings
Aug 5, 2026 (est.)

Risks & Fundamentals

Every setup carries risk. Here's what could move AMGN against you, plus the key stats that frame any position.

Beta
0.7
Market cap
~$155B
Risk level
Low risk
Next earnings
Aug 5, 2026 (est.)
Key risks to monitor
  • 1.GLP-1 obesity market is intensely competitive — Eli Lilly and Novo Nordisk have first-mover advantages that are hard to overcome
  • 2.Biosimilar competition to core products (Enbrel, Prolia) continues to erode volume in legacy franchises
  • 3.Horizon acquisition leverage elevated the balance sheet; integration execution risk remains
These are real risks to the long thesis, not a recommendation to short. Stoptions setups are short-dated and stop-protected; size accordingly.

AMGN Options Setup — Frequently Asked Questions

Is AMGN a good options trade today?+

Amgen Inc. (AMGN) currently has an Amora Edge Score of 71/100, ranking it top 32% of today's scan. This composite score is built from four sub-signals — EMA cross, RSI zone, relative strength vs SPY, and volume surge — each scored 0–25. The current read is a bullish setup, so the algorithm is positioned bullish (calls / call debit spreads). A score above 65 typically warrants a trade card with stop and target; below that, the setup is on the watchlist but not actionable.

What is AMGN's win rate on Stoptions.ai setups?+

AMGN's historical win rate on closed Stoptions setups is 69%. Win rate is calculated as the percentage of past AMGN trade cards that hit their target price before stopping out. Win rate is most meaningful once a ticker has 10+ closed trades — individual ticker rates can be noisy at smaller samples. Our portfolio-wide win rate across all closed trades is the more stable benchmark.

What strike and expiry does Stoptions.ai suggest for AMGN?+

The strike and expiry are shown on the trade card at the top of this page when the setup is active. Stoptions.ai algorithmically selects strikes targeting delta 0.35–0.45 and expirations 30–45 days out, adjusted for current implied volatility rank (IVR). When IVR is high, the system favors call debit spreads to limit vega risk; when IVR is low, single-leg long calls are preferred. The card includes the contract symbol, mid-price entry, stop, and target.

How often is the AMGN setup updated?+

Every 72 hours we refresh AMGN's Amora Edge Score and trade card. The underlying scan runs daily at 9:00 AM ET (pre-market) and 9:30 AM ET (post-open), so any new signal change is reflected within one trading session. If AMGN drops below the entry threshold or the regime shifts (e.g., SPY enters a confirmed bear), the trade card is replaced with a "no setup" notice automatically.

What does the Amora Edge Score measure for AMGN?+

The Amora Edge Score is a 0–100 composite of four technical sub-signals applied to AMGN: (1) EMA cross — is the 20-day above the 50-day with both trending up? (2) RSI zone — is momentum in the 50–70 sweet spot, or extended/weak? (3) Relative strength vs SPY — is AMGN outperforming the market over 20 sessions? (4) Volume surge — is participation above the 20-day average? Each sub-signal contributes 0–25 points. AMGN currently scores 71.

How does AMGN compare to other Large-Cap Biotechnology & Drug Development setups?+

AMGN's sector rank and percentile against other Large-Cap Biotechnology & Drug Development tickers we track is shown on the /tickers index — sortable by Amora Edge Score, win rate, or sector. For direct comparison, see the "Related Large-Cap Biotechnology & Drug Development Options Setups" panel above. When multiple tickers in the same sector are scoring 80+, the algorithm flags the cluster as a sector rotation signal and may upweight position sizing.

Educational content only — not personalized investment advice. Options carry substantial risk.

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